The optimal option for each individual varies; however, several drugs can help alleviate excessive daytime drowsiness in people with narcolepsy. A popular first-line wakefulness-promoting medication that is frequently recommended to treat narcolepsy is called Modvigil 200 (modafinil 200 mg). Pitolisant or sodium oxybate, which can relieve symptoms like cataplexy, and solriamfetol, which some research indicates is even more helpful for promoting drowsiness, are other good choices. There isn't a single medication that is "most effective" for treating narcolepsy symptoms; instead, a professional should lead treatment. All of these are far more effective than placebo.